Cortisone is a hormone secreted by the adrenal gland, which is a small gland near the
kidney. This gland secretes different kinds of hormones that regulate body processes.
Cortisone is primarily used therapeutically for its anti-inflammatory properties. It is the
body's most powerful natural resistance to inflammation.
Inflammation - swelling causes inability to move joints, and is a natural mechanism of
immobilization. Swelling initiates pain to cause us to avoid using or touching the painful
area, so as to rest the involved part.
However, inflammation itself may be potentially harmful. Fibrous bonds limit joint
movement and scar tissue hampers the function of organs.
For localized injections, manmade cortisone-like preparations are used. These
compounds enhance the anti-inflammatory properties and decreased the other less
desireable metabolic properties of cortisone.
Indications:
Joint inflammatory conditions (osteoarthritis, rheumatoid arthritis, gouty arthritis, and
others)
Bursitis
Peri-arthritis
Tendonitis: inflammation of the tendon or its sheath
Neuritis: inflammation of a nerve or its surrounding structures i.e. neuroma.
Fibrositis: inflammation of muscle or its surrounding tissue.
Reduction of scar tissue
Dermatologic diseases
Symptomatic improvement can occur within the first 24 hours; improvement in pain and
stiffness is sometimes dramatic. A post injection reaction is possible, but usually subsides
within 2-3 days. Maximal relief from pain and swelling is usually attained in 3 days and may
continue up to 2 weeks or longer.
Corticosteroids are used locally (in joints or other soft tissue structures), and sometimes
are mixed with local aesthetic for symptomatic relief.
Local injections of a small amount of a cortico-steroid have very few, and rarely adverse
reactions compared to long term cortisone therapy. A small amount is injected in a small,
limited local area, and is usually fully absorbed in 2 weeks or less. They are usually spaced
no closer than 7-14 days apart.
